Reduction in blood glucose, glycosylated haemoglobin and glycosylated plasma proteins ¹¹. In one study using Gymnema Sylvestre extract (400 mg/day) for 18-20 months reduced blood glucose, glycosylated haemoglobin and glycosylated plasma proteins, allowed reduced conventional drug dosage for 22 Type 2 diabetic patients. While receiving Gymnema Sylvestre supplementation, the patients showed a significant reduction in blood glucose, glycosylated haemoglobin and glycosylated plasma proteins, and conventional drug dosage could be decreased. Five of the 22 diabetic patients were able to discontinue their conventional drug and maintain their blood glucose homeostasis with GS4 alone. These data suggest that the beta cells may be regenerated/repaired in Type 2 diabetic patients on GS4 supplementation. This is supported by the appearance of raised insulin levels in the serum of patients after GS4 supplementation.